Description

4-tert-Butyl-1H-Imidazole-2-Thiol is a specialized heterocyclic building block featuring a thiol group and a bulky tert-butyl substituent. This molecular structure makes it a valuable intermediate for synthesizing complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new fungicides, herbicides, or plant growth regulators.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Potential monomer or additive in the production of polymers with specific electronic or mechanical properties.
• Chemical Research: A versatile reagent for organic synthesis, enabling the introduction of the imidazole-thiol moiety into larger molecular frameworks.

Basic Information

Product Name	4-tert-Butyl-1H-Imidazole-2-Thiol
CAS No.	14395-90-5
Molecular Formula	C7H12N2S
Molecular Weight	156.25 g/mol
Synonyms	4-tert-Butyl-1H-imidazole-2-thiol; 2-Mercapto-4-tert-butylimidazole; 4-(1,1-Dimethylethyl)-1H-imidazole-2-thiol; 4-tert-Butyl-2-mercaptoimidazole; NSC 163063; 2-Thiol-4-tert-butylimidazole; 4-tert-Butylimidazole-2-thione (tautomeric form)
EINECS	Contact for details

Quality Control

Every batch of 4-tert-Butyl-1H-Imidazole-2-Thiol is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or titration), identity confirmation (by IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.