Description

2-Nitro-4-(Trifluoromethyl)Thiophenol is a specialized aromatic thiol derivative characterized by its nitro and trifluoromethyl substituents. This compound serves as a versatile and high-value building block in advanced organic synthesis, particularly for introducing sulfur-containing functional groups with electron-withdrawing properties. It is primarily sought after by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, especially those targeting specific enzyme inhibition or requiring bioisosteric replacement.
• Agrochemical Synthesis: Used in developing novel herbicides, fungicides, and insecticides where the thiophenol moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Polymer and Material Science: Incorporated as a monomer or modifier to impart specific properties like adhesion, chemical resistance, or electronic characteristics to advanced polymers.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating complex molecular architectures.

Basic Information

Product Name	2-Nitro-4-(Trifluoromethyl)Thiophenol
CAS No.	14371-82-5
Molecular Formula	C7H4F3NO2S
Molecular Weight	223.17 g/mol
Synonyms	2-Nitro-α,α,α-trifluoro-p-thiocresol; 4-(Trifluoromethyl)-2-nitrobenzenethiol; 2-Nitro-4-trifluoromethylthiophenol; 2-Nitro-4-(trifluoromethyl)benzenethiol; Benzenethiol, 2-nitro-4-(trifluoromethyl)-; p-(Trifluoromethyl)-o-nitrothiophenol
EINECS	Contact for details

Quality Control

Every batch of 2-Nitro-4-(Trifluoromethyl)Thiophenol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure consistency, purity, and traceability for your critical synthesis workflows. A detailed Certificate of Analysis (COA) including results for assay, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.