Description

5,8-Dihydroxypsoralen is a naturally occurring furanocoumarin derivative, recognized for its unique photochemical properties. This compound is a critical intermediate and active ingredient in the development of specialized pharmaceuticals and research chemicals. It is primarily sought by manufacturers and research institutions in the pharmaceutical, cosmetic, and life science sectors for applications in phototherapy and biochemical research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of psoralen-based drugs used in PUVA (Psoralen + UVA) therapy for skin conditions like psoriasis and vitiligo.
• Photochemotherapy Research: Used in biochemical and dermatological research to study mechanisms of photosensitization, DNA intercalation, and cell cycle regulation under UV light.
• Cosmetic Ingredient Research: Investigated for potential use in controlled photodynamic applications and as a model compound for studying skin-lightening or depigmentation agents.
• Analytical Reference Standard: Serves as a high-purity standard in HPLC, LC-MS, and NMR for quality control and method development in pharmaceutical analysis.
• Biochemical Probe: Utilized in plant biology and ecology research to study natural defense mechanisms in plants, as psoralens are produced as phytoalexins.

Basic Information

Product Name	5,8-Dihydroxypsoralen
CAS No.	14348-23-3
Molecular Formula	C₁₁H₆O₅
Molecular Weight	218.16 g/mol
Synonyms	5,8-Dihydroxypsoralen; 5,8-Dihydroxyfuro[3,2-g]chromen-7-one; 5,8-Dihydroxy-7H-furo[3,2-g][1]benzopyran-7-one; Psoralen-5,8-diol; 5,8-Dihydroxy-7H-furo[3,2-g]chromen-7-one; Isopimpinellin derivative; 5,8-DiOH-psoralen
EINECS	Contact for details

Quality Control

Our 5,8-Dihydroxypsoralen is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by FT-IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive compound from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.