Description

3-Mercapto-2-(Methylamino)Propanoic Acid Hydrochloride is a high-purity organic compound featuring both a thiol and an amino acid moiety, making it a versatile chiral building block for advanced synthesis. Its primary value lies in its role as a key intermediate in the development of pharmaceuticals and fine chemicals, particularly for creating molecules with specific stereochemistry and biological activity. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and metabolic diseases.
• Peptide Mimetic Research: Used to incorporate modified cysteine or penicillamine-like structures into peptides to enhance stability, bioavailability, or receptor binding affinity.
• Ligand Synthesis for Catalysis: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Bioconjugation Chemistry: The thiol group allows for site-specific conjugation in the development of antibody-drug conjugates (ADCs) or other bioconjugates.
• Agrochemical Synthesis: Employed as a building block in the creation of novel herbicides, fungicides, or plant growth regulators with specific chiral activity.
• Chemical Biology Probes: Useful for synthesizing probes that target enzymes or receptors involving thiol or amino acid interactions.

Basic Information

Product Name	3-Mercapto-2-(Methylamino)Propanoic Acid Hydrochloride
CAS No.	14344-46-8
Molecular Formula	C5H12ClNO2S
Molecular Weight	185.67 g/mol
Synonyms	2-Methylamino-3-mercaptopropanoic acid hydrochloride; 3-Mercapto-N-methylalanine hydrochloride; D,L-3-Mercapto-2-(methylamino)propionic acid hydrochloride; Methylcysteine hydrochloride (uncommon); (RS)-2-(Methylamino)-3-sulfanylpropanoic acid hydrochloride; 3-Thio-2-(methylamino)propionic acid hydrochloride; (2RS)-2-(Methylamino)-3-mercaptopropanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Mercapto-2-(Methylamino)Propanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccant or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.