Description

Dl-Glutamic-2,3,3,4,4-D5 Acid is a stable isotope-labeled analog of glutamic acid, where five hydrogen atoms are replaced with deuterium at specific positions. This compound is essential for advanced research and analytical applications requiring precise molecular tracing and quantification. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for use as an internal standard in mass spectrometry, metabolic pathway studies, and drug development research.

Application

• Internal Standard for Mass Spectrometry (MS): Provides high-purity reference material for accurate quantification of glutamic acid in complex biological matrices like plasma, urine, and tissue samples.
• Metabolic Research & Tracer Studies: Used to investigate glutamine/glutamate metabolism, neurotransmitter cycling, and energy pathways in cellular and in vivo models.
• Pharmaceutical Development: Serves as a critical tool in pharmacokinetic (PK) and pharmacodynamic (PD) studies for drug candidates targeting glutamate-related pathways.
• Clinical Diagnostics: Enables precise measurement of glutamate levels in clinical samples for research into neurological disorders and metabolic conditions.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Acts as a deuterated standard to aid in spectral analysis and method development.
• Biochemical Assay Development: Used in the calibration and validation of enzymatic assays and analytical methods for amino acid analysis.

Basic Information

Item	Detail
Product Name	Dl-Glutamic-2,3,3,4,4-D5 Acid
CAS No.	14341-79-8
Molecular Formula	C5H4D5NO4
Molecular Weight	152.15 g/mol (for deuterated form)
Synonyms	DL-Glutamic-2,3,3,4,4-d5 Acid; (2,3,3,4,4-D5)DL-Glutamic Acid; Glutamic Acid-d5 (DL-form); Deuterated DL-Glutamic Acid; (±)-2-Aminopentanedioic-2,3,3,4,4-d5 Acid; DL-Glu-d5; 2,3,3,4,4-Pentadeutero-DL-glutamic Acid; DL-2-Aminoglutaric-2,3,3,4,4-d5 Acid
EINECS	Contact for details

Quality Control

Every batch of Dl-Glutamic-2,3,3,4,4-D5 Acid is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, verified by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic abundance, and analytical results is provided with each shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.