Description

Dl-Aspartic-2,3,3-D3 Acid is a stable isotope-labeled analog of the amino acid aspartic acid, specifically deuterated at the 2,3,3 positions. This compound is essential for advanced research and analytical applications where precise molecular tracking and quantification are required. It is primarily utilized by scientists and manufacturers in the fields of pharmaceutical development, metabolic research, and analytical chemistry.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference standard in LC-MS and GC-MS analysis for accurate measurement of endogenous aspartic acid levels in complex biological matrices.
• Metabolic Pathway Tracing: Used in isotope-labeling studies to investigate metabolic fluxes, protein synthesis rates, and the citric acid cycle dynamics in biological systems.
• Pharmaceutical Research & Development: Employed in the synthesis and pharmacokinetic (PK) studies of deuterated drug candidates, leveraging the kinetic isotope effect for improved metabolic stability.
• Nutritional Science Research: Facilitates studies on amino acid absorption, utilization, and turnover in clinical and preclinical nutritional models.
• Biochemical Reagent: Acts as a specialized building block or tracer in enzymatic assays and in vitro biochemical reaction studies.
• NMR Spectroscopy: Useful as a deuterated probe in nuclear magnetic resonance spectroscopy to simplify spectra and study molecular structure and dynamics.

Basic Information

Product Name	Dl-Aspartic-2,3,3-D3 Acid
CAS No.	14341-75-4
Molecular Formula	C4H4D3NO4
Molecular Weight	136.12 g/mol
Synonyms	DL-Aspartic-2,3,3-d3 Acid; (2,3,3-2H3)-DL-Aspartic Acid; DL-Aspartic Acid-2,3,3-d3; Deuterated DL-Aspartic Acid; (±)-2-Aminosuccinic-2,3,3-d3 Acid; Aminosuccinic Acid-d3; 2,3,3-Trideutero-DL-aspartic Acid; DL-Aspartic Acid (2,3,3-D3)
EINECS	Contact for details

Quality Control

Every batch of Dl-Aspartic-2,3,3-D3 Acid is produced and analyzed under strict quality management protocols. We guarantee high chemical purity and isotopic enrichment, supported by comprehensive analytical data including NMR, MS, and HPLC. A Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and specific tests is provided with each shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.