Description

Ethyl 3-Bromopropionate-2,2,3,3-D4 is a deuterated isotopologue of ethyl 3-bromopropionate, a valuable building block in synthetic organic chemistry. This compound is specifically designed for applications requiring stable isotope labeling, such as in mechanistic studies, metabolic research, and as an internal standard in analytical methods. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically labeled intermediates for precise and reliable results.

Application

• Pharmaceutical Research & Development: Used as a deuterium-labeled intermediate in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for drug discovery, metabolic pathway tracing, and pharmacokinetic studies.
• Analytical Chemistry Standards: Serves as a critical internal standard in quantitative analytical techniques like Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for accurate compound quantification.
• Mechanistic & Isotope Effect Studies: Employed in academic and industrial research to investigate chemical reaction mechanisms and kinetic isotope effects (KIEs) due to the deuterium substitution.
• Agrochemical Synthesis: Acts as a specialized precursor in the development of labeled agrochemicals for environmental fate studies and residue analysis.
• Material Science: Utilized in the synthesis of deuterated polymers or organic electronic materials where specific isotopic composition can alter physical properties.
• NMR Spectroscopy: Functions as a useful reagent or solvent in Nuclear Magnetic Resonance (NMR) spectroscopy, benefiting from the absence of proton signals at the deuterated positions.

Basic Information

Item	Detail
Product Name	Ethyl 3-Bromopropionate-2,2,3,3-D4
CAS No.	14341-55-0
Molecular Formula	C5H5D4BrO2
Molecular Weight	197.06 g/mol (approx.)
Synonyms	Ethyl 3-Bromopropionate-d4; 3-Bromopropionic Acid Ethyl Ester-d4; Ethyl β-Bromopropionate-d4; [2,2,3,3-2H4]Ethyl 3-Bromopropanoate; Deuterated Ethyl 3-Bromopropionate; NSC 9376-d4; Ethyl 3-Bromopropanoate-2,2,3,3-d4
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromopropionate-2,2,3,3-D4 is produced under strict quality management systems. Each batch undergoes comprehensive analysis to ensure high chemical purity and isotopic enrichment, typically exceeding 98% chemical purity and 98 atom % D. Standard testing includes assay (by GC or NMR), isotopic purity determination (by MS or NMR), and identification. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.