Description

4H-Thieno[3,2-b]pyrrol-5(6H)-one is a high-purity heterocyclic organic compound featuring a fused thiophene-pyrrolone structure. This specialized chemical building block is valued for its unique molecular architecture, which is critical for advanced research and synthesis in medicinal chemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs) and other high-value intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Organic Synthesis Building Block: Used in constructing complex heterocyclic frameworks for agrochemicals, dyes, and functional materials.
• Academic & Industrial Research: Serves as a reference standard and starting material in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential application in the synthesis of organic semiconductors and photoconductive materials due to its electron-rich fused ring system.

Basic Information

Product Name	4H-Thieno[3,2-b]pyrrol-5(6H)-one
CAS No.	14298-19-2
Molecular Formula	C6H5NOS
Molecular Weight	139.17 g/mol
Synonyms	4H-Thieno[3,2-b]pyrrol-5-one; 5H-Thieno[3,2-b]pyrrol-6-one; Thieno[3,2-b]pyrrol-5(6H)-one; 4H-Thieno[3,2-b]pyrrol-5(6H)-one; 14298-19-2; Thienopyrrolone; 5-Oxo-4,5-dihydrothieno[3,2-b]pyrrole
EINECS	Contact for details

Quality Control

Our production of 4H-Thieno[3,2-b]pyrrol-5(6H)-one adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.