Description

2-Bromomethylthiophene-5-Carboxylic Acid Ethyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive bromomethyl and ester functional groups, which enable efficient derivatization and incorporation into complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or building block for conductive polymers, organic semiconductors, and advanced functional materials.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-Bromomethylthiophene-5-Carboxylic Acid Ethyl Ester
CAS No.	14282-72-5
Molecular Formula	C9H9BrO2S
Molecular Weight	261.14 g/mol
Synonyms	Ethyl 2-(bromomethyl)thiophene-5-carboxylate; 5-(Ethoxycarbonyl)-2-thienylmethyl bromide; 2-Thiophenecarboxylic acid, 2-(bromomethyl)-, ethyl ester; 2-Bromomethyl-5-ethoxycarbonylthiophene; Ethyl 5-(bromomethyl)thiophene-2-carboxylate (common numbering); 2-Bromomethyl-5-thiophenecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Bromomethylthiophene-5-Carboxylic Acid Ethyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles by HPLC, GC, NMR, and other relevant methods is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98.0-99.5%)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.