Description

4-(Hydroxymethyl)Thiophene-2-Carboxylic Acid is a versatile heterocyclic building block featuring both a carboxylic acid and a hydroxymethyl functional group on a thiophene core. This bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is particularly valuable for pharmaceutical chemists and material scientists working on active pharmaceutical ingredients (APIs), functional polymers, and liquid crystal materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for creating thiophene-based derivatives used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Used to introduce thiophene units into polymer backbones or as a cross-linking agent to enhance material properties.
• Agrochemical Research: Employed in the synthesis of novel compounds for crop protection and agrochemical development.
• Coordination Chemistry & Ligand Design: The carboxylic acid group allows it to act as a ligand for metal complexes in catalysis and material science.
• Chemical Research & Development: A versatile starting material for custom synthesis and the exploration of new chemical entities in academic and industrial labs.

Basic Information

Product Name	4-(Hydroxymethyl)Thiophene-2-Carboxylic Acid
CAS No.	14282-65-6
Molecular Formula	C6H6O3S
Molecular Weight	158.18 g/mol
Synonyms	2-Thiophenecarboxylic acid, 4-(hydroxymethyl)-; 4-(Hydroxymethyl)-2-thiophenecarboxylic acid; 4-Hydroxymethylthiophene-2-carboxylic acid; 2-Carboxy-4-hydroxymethylthiophene; 4-(Hydroxymethyl)thiophene-2-carboxylic acid; 4-Hydroxymethyl-2-thiophenecarboxylic acid; (4-Hydroxymethyl-thiophen-2-yl)-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Thiophene-2-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.