Description

5-Chloro-1-Pentyne is a versatile halogenated alkyne building block, essential for advanced organic synthesis. Its terminal alkyne and reactive chloroalkyl functionalities make it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and novel drug candidates via Sonogashira and other cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or precursor for functional polymers, dendrimers, and advanced organic materials.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Organic Synthesis Reagent: A fundamental reagent for introducing pentynyl and chloropentyl groups into target molecules in research and development.
• Chemical Biology Probes: Used in click chemistry applications to create labeled probes for studying biological systems.

Basic Information

Product Name	5-Chloro-1-Pentyne
CAS No.	14267-92-6
Molecular Formula	C5H7Cl
Molecular Weight	102.56 g/mol
Synonyms	1-Chloro-4-pentyne; 4-Pentyn-1-yl chloride; Chloropentyne; Pent-4-yn-1-yl chloride; 5-Chloropentyne; 5-Chloro-1-pentyne; 4-Pentyne-1-yl chloride
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-Pentyne is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. Containers should be kept tightly sealed when not in use to prevent evaporation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.