Description

Dl-Phenylalanine-2-D1 CAS NO 14246-24-3 is a deuterium-labeled analog of the essential amino acid phenylalanine, where a hydrogen atom at the 2-position is replaced by a deuterium atom. This isotopic labeling makes it a crucial tool compound for advanced research in metabolic studies, proteomics, and pharmaceutical development. It is primarily utilized by scientists and manufacturers in the fields of analytical chemistry, life sciences, and drug discovery who require stable isotope-labeled internal standards for mass spectrometry and NMR spectroscopy.

Application

• As a stable isotope-labeled internal standard for the precise quantification of phenylalanine and related metabolites via LC-MS/MS and GC-MS.
• In metabolic pathway tracing and pharmacokinetic studies to investigate amino acid metabolism and drug disposition.
• For use in proteomics research, particularly in the development of quantitative methods for protein analysis and biomarker discovery.
• As a key building block in the synthesis of deuterium-labeled peptides and other bioactive molecules for research purposes.
• In NMR spectroscopy as a probe to study molecular structure, dynamics, and interactions without significant isotopic interference.
• For quality control and method development in pharmaceutical analysis to ensure accuracy and regulatory compliance.

Basic Information

Product Name	Dl-Phenylalanine-2-D1
CAS No.	14246-24-3
Molecular Formula	C9H10DNO2
Molecular Weight	166.20 g/mol (approx.)
Synonyms	DL-Phenylalanine-2-d1; (RS)-2-Amino-3-phenylpropionic-2-d1 acid; (±)-2-Amino-3-phenylpropionic-2-d1 acid; Phenylalanine-2-d1, DL-; 2-Deuterio-DL-phenylalanine; DL-2-Deuteriophenylalanine; Phenylalanine (2-d1); DL-α-Amino-β-phenylpropionic-α-d1 acid
EINECS	Contact for details

Quality Control

Our Dl-Phenylalanine-2-D1 is produced under controlled conditions to ensure high chemical purity and isotopic enrichment. Each batch undergoes rigorous analytical testing, including HPLC for chemical purity and MS/NMR for isotopic purity verification. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment, and impurity profiles is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.