Description

2-(2-Bromo-Phenyl)-5-Chloro-1H-Benzoimidazole is a halogenated benzimidazole derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromo and chloro substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzimidazole core.
• Material Science: Acts as a monomer or functional unit in the creation of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromoaryl group.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in university and corporate research laboratories.

Basic Information

Product Name	2-(2-Bromo-Phenyl)-5-Chloro-1H-Benzoimidazole
CAS No.	14225-83-3
Molecular Formula	C₁₃H₈BrClN₂
Molecular Weight	307.57 g/mol
Synonyms	2-(2-Bromophenyl)-5-chloro-1H-benzimidazole; 5-Chloro-2-(2-bromophenyl)-1H-benzimidazole; 1H-Benzimidazole, 2-(2-bromophenyl)-5-chloro-; 2-(2-Bromophenyl)-5-chlorobenzimidazole; 5-Chloro-2-(o-bromophenyl)benzimidazole; Benzimidazole, 2-(2-bromophenyl)-5-chloro-; 14225-83-3 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Bromo-Phenyl)-5-Chloro-1H-Benzoimidazole is produced and tested under a strict quality management system to ensure consistency and reliability for your research and development processes. We provide comprehensive analytical data including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.