Description

4-Methoxytoluene-Alpha,Alpha,α-D3 is a deuterated isotopologue of 4-methoxytoluene (p-methylanisole), where three hydrogen atoms on the methyl group are replaced by deuterium. This high-purity, labeled compound is critical for applications requiring precise molecular tracking and reduced metabolic interference. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for use as an internal standard, a tracer in metabolic studies, and a building block in deuterated fine chemicals.

Application

• Pharmaceutical Research & Development: Serves as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of p-methylanisole and related compounds in bioanalytical studies.
• Metabolic Pathway Tracing: Used as a deuterium tracer to investigate drug metabolism, pharmacokinetics, and biochemical pathways, leveraging the kinetic isotope effect for more detailed mechanistic insights.
• Deuterated Fine Chemical Synthesis: Acts as a key synthon or precursor in the synthesis of more complex deuterated molecules for use in organic electronics, specialty polymers, and advanced material science.
• Agrochemical Analysis: Employed as a reference standard in environmental and residue analysis for pesticides or herbicides where p-methoxytoluene is a metabolite or structural component.
• NMR Spectroscopy Solvent & Reagent: Useful in nuclear magnetic resonance (NMR) spectroscopy as a deuterated solvent additive or a probe for studying molecular interactions and reaction mechanisms.

Basic Information

Product Name	4-Methoxytoluene-Alpha,Alpha,α-D3
CAS No.	14202-49-4
Molecular Formula	C8H7D3O
Molecular Weight	125.20 g/mol
Synonyms	p-Methylanisole-d3; 1-Methoxy-4-(trideuteriomethyl)benzene; 4-(Trideuteriomethyl)anisole; Methyl-d3 p-tolyl ether; Anisole, 4-(trideuteriomethyl)-; p-(Trideuteriomethyl)anisole; Deuterated p-Methylanisole; 4-Methoxy(alpha,alpha,α-D3)toluene
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxytoluene-Alpha,Alpha,α-D3 is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, GC-MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles is provided with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (D3)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.