Description

trans-4,5-Dihydroxy-1,2-Dithiane is a high-purity, sulfur-containing heterocyclic compound featuring a unique dithiane ring structure with vicinal hydroxyl groups. This specific stereochemistry and functional group arrangement make it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Ligand and Catalyst Precursor: Used in the synthesis of specialized ligands for asymmetric catalysis and metal complexation, enabling highly selective chemical transformations.
• Flavor and Fragrance Chemistry: Acts as a precursor for synthesizing complex sulfur-containing aroma compounds, contributing to savory or roasted flavor profiles in high-value applications.
• Agrochemical Research: Employed as a building block in the development of new crop protection agents and herbicides, leveraging its unique heterocyclic core.
• Material Science: Investigated for use in creating novel polymers and functional materials with specific optical or electronic properties derived from the dithiane unit.
• Academic and R&D Laboratories: Utilized in fundamental chemical research for studying reaction mechanisms, stereochemistry, and the development of new synthetic methodologies.

Basic Information

Product Name	trans-4,5-Dihydroxy-1,2-Dithiane
CAS No.	14193-38-5
Molecular Formula	C4H8O2S2
Molecular Weight	152.23 g/mol
Synonyms	(4R,5R)-4,5-Dihydroxy-1,2-dithiane; (4S,5S)-4,5-Dihydroxy-1,2-dithiane; meso-4,5-Dihydroxy-1,2-dithiane; 1,2-Dithiane-4,5-diol, trans-; DTT diol (Dithiothreitol precursor); Erythro-1,2-dithiane-4,5-diol; 4,5-Dihydroxy-1,2-dithiane (racemic)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and industrial use. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specific results for purity, chiral purity, and impurity profiles are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified for high-purity grades. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.