Description

1-Iodo-4,4,4-Trifluoro-3,3-Bis(Trifluoromethyl)Butane is a highly fluorinated organic iodide building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a reactive iodine atom adjacent to a perfluoro-tert-butyl group, makes it a valuable precursor for introducing fluorinated segments into target molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated analogs of drug candidates to improve bioavailability and patent life.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides where fluorine incorporation enhances activity and environmental persistence.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty fluoropolymers with unique surface properties and chemical resistance.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic display materials, influencing dielectric constant and alignment.
• Catalyst Ligand Modification: Used to prepare sophisticated fluorinated ligands for transition metal catalysts, potentially altering selectivity and activity.
• Radical Chemistry Reagent: Acts as a source of iodoperfluoro-tert-butyl radicals for studying and applying novel radical reaction pathways.

Basic Information

Product Name	1-Iodo-4,4,4-Trifluoro-3,3-Bis(Trifluoromethyl)Butane
CAS No.	14115-45-8
Molecular Formula	C6H4F9I
Molecular Weight	397.99 g/mol
Synonyms	1-Iodoperfluoro-tert-butane; (Perfluoro-tert-butyl)iodomethane; 1-Iodo-3,3-bis(trifluoromethyl)-4,4,4-trifluorobutane; (Trifluoromethyl)(iodo)bis(trifluoromethyl)methane; PFTB-I; Perfluoro-tert-butyl iodide; 1,1,1,4,4,4-Hexafluoro-2-iodo-2-(trifluoromethyl)-3-(trifluoromethyl)butane
EINECS	Contact for details

Quality Control

Our 1-Iodo-4,4,4-Trifluoro-3,3-Bis(Trifluoromethyl)Butane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures material integrity for your sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, ideally at 2-8°C (refrigerated) to minimize volatility and degradation. Due to its highly volatile nature, allow the container to reach ambient temperature before opening to prevent moisture ingress and pressure buildup. Keep away from strong bases and reactive metals.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~2.1 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.