Description

1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a versatile heterocyclic amine salt that serves as a critical building block in advanced organic synthesis. Its value lies in its role as a key precursor for pharmaceuticals and fine chemicals, enabling the construction of complex molecular architectures. This compound is essential for research chemists and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of various bioactive molecules, including potential central nervous system (CNS) agents, antitumor compounds, and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the tetrahydroisoquinoline scaffold for biological activity.
• Organic Synthesis Building Block: Employed in the construction of complex natural product analogs and other nitrogen-containing heterocycles due to its reactive amine functionality.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers, ligands for catalysis, and advanced organic materials.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for methodological studies and new reaction development.

Basic Information

Product Name	1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	14099-81-1
Molecular Formula	C9H12ClN
Molecular Weight	169.65 g/mol
Synonyms	1,2,3,4-Tetrahydroisoquinoline HCl; THIQ Hydrochloride; 1,2,3,4-Tetrahydroisoquinolinium Chloride; 3,4-Dihydro-1H-isoquinoline Hydrochloride; 1,2,3,4-Tetrahydroisoquinoline Monohydrochloride; Isoquinoline, 1,2,3,4-tetrahydro-, hydrochloride; NSC 172112
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.