Description

Ammonium-D4 Deuteroxide is a deuterated form of ammonium hydroxide, where the hydrogen atoms are replaced with the stable isotope deuterium. This compound is critical for applications requiring isotopic labeling, such as NMR spectroscopy and mechanistic studies in organic and pharmaceutical chemistry. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in advanced chemical synthesis and spectroscopic analysis.

Application

• NMR Spectroscopy: Used as a deuterated solvent or reagent for locking and shimming in nuclear magnetic resonance (NMR) experiments.
• Isotopic Labeling Studies: Serves as a source of deuterium for tracing reaction mechanisms and metabolic pathways in pharmaceutical research.
• Organic Synthesis: Acts as a strong base in specialized deuteration reactions to synthesize deuterium-labeled compounds.
• Analytical Chemistry: Employed as a reagent in mass spectrometry and other analytical techniques for calibration and method development.
• Pharmaceutical Intermediate Production: Used in the synthesis of active pharmaceutical ingredients (APIs) where deuterium incorporation is desired for improved metabolic stability.
• Material Science Research: Applied in the study of surface chemistry and catalysis involving deuterium exchange.

Basic Information

Product Name	Ammonium-D4 Deuteroxide
CAS No.	14067-21-1
Molecular Formula	ND4OD
Molecular Weight	41.08 g/mol
Synonyms	Deuterated Ammonium Hydroxide; Ammonium Hydroxide-d5; Deuterium Oxide Solution of Ammonia-d4; ND4OD; Ammonia-d4 Deuteroxide; Heavy Ammonia Solution; Deuterated Aqueous Ammonia
EINECS	Contact for details

Quality Control

Our Ammonium-D4 Deuteroxide is produced and tested under stringent quality management systems. Each batch is analyzed to ensure high isotopic purity and chemical consistency, with specifications typically meeting or exceeding research-grade standards. Certificates of Analysis (COA) detailing isotopic enrichment (D-atom %), assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area. Due to its highly volatile nature, keep the container tightly sealed when not in use and away from heat and sources of ignition. Recommended storage temperature is 2-8°C to minimize decomposition and volatilization.

Specification

Item	Specification
Appearance	Colorless solution
Identification (IR)	Conforms
Deuterium Isotopic Purity (NMR)	≥ 99.5 atom % D
Assay (as ND4OD)	20-30 wt.% in D2O
pH	> 13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.