Description

(3Ar,10Br)-2,3,4,5,11,12-Hexahydro-5β-Hydroxy-14-Oxo-6H,13Aαh-3Aα,5Aα-Ethano-4β,11β-Methano-1H-Indolizino[8,1-Cd]Carbazole-6-Carboxylic Acid Methyl Ester is a complex, high-purity alkaloid derivative with a unique polycyclic framework. This compound serves as a critical advanced intermediate in pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents. It is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable access to structurally sophisticated building blocks.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel alkaloid-based drugs and bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Process Chemistry: Serves as a benchmark or starting material for scaling up synthetic routes in pilot plants and manufacturing.
• Academic Research: Employed in universities and research institutes for studying complex organic synthesis methodologies and natural product analogs.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Probe Development: Potential use in creating specialized probes for investigating biological pathways and enzyme interactions.

Basic Information

Product Name	(3Ar,10Br)-2,3,4,5,11,12-Hexahydro-5β-Hydroxy-14-Oxo-6H,13Aαh-3Aα,5Aα-Ethano-4β,11β-Methano-1H-Indolizino[8,1-Cd]Carbazole-6-Carboxylic Acid Methyl Ester
CAS No.	14058-43-6
Molecular Formula	C24H24N2O4
Molecular Weight	404.46 g/mol
Synonyms	Methyl (3aR,10bR)-2,3,3a,4,5,11-hexahydro-5b-hydroxy-14-oxo-6H,13aαH-3aα,5aα-ethano-4β,11β-methano-1H-indolizino[8,1-cd]carbazole-6-carboxylate; 5b-Hydroxy-14-oxo-3a,4,5,5a,6,11,12,13a-octahydro-3aα,5aα-ethano-4β,11β-methano-1H-indolizino[8,1-cd]carbazole-6-carboxylic acid methyl ester; A complex indolizino-carbazole alkaloid ester derivative.
EINECS	Contact for details

Quality Control

Our (3Ar,10Br)-2,3,4,5,11,12-Hexahydro-5β-Hydroxy-14-Oxo-6H,13Aαh-3Aα,5Aα-Ethano-4β,11β-Methano-1H-Indolizino[8,1-Cd]Carbazole-6-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.