Description

Borane-Tetrahydrofuran Complex (CAS NO 14044-65-6) is a versatile and widely used reagent, primarily serving as a powerful and selective reducing agent in organic synthesis. Its value lies in its ability to facilitate key transformations, such as the hydroboration of alkenes and alkynes and the reduction of carbonyl groups, under mild conditions. This makes it an indispensable tool for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where precise control over stereochemistry and functional group manipulation is critical.

Application

• Hydroboration Reactions: A key reagent for the stereoselective synthesis of organoboranes from alkenes and alkynes, which are pivotal intermediates in Suzuki-Miyaura cross-coupling and other transformations.
• Carbonyl Reduction: Selectively reduces aldehydes, ketones, and acid chlorides to their corresponding alcohols, often with high chemoselectivity.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs) for constructing complex molecular architectures.
• Asymmetric Synthesis: Employed in conjunction with chiral catalysts or auxiliaries for the production of enantiomerically enriched compounds.
• Polymer Chemistry: Acts as a catalyst or initiator in certain polymerization processes and for modifying polymer surfaces.
• Fine Chemical Manufacturing: Essential for synthesizing specialty chemicals, flavors, fragrances, and advanced materials.

Basic Information

Product Name	Borane-Tetrahydrofuran Complex
CAS No.	14044-65-6
Molecular Formula	C4H8O·BH3 / BH3·C4H8O
Molecular Weight	85.94 g/mol
Synonyms	Borane-THF Complex; BH3-THF; Tetrahydrofuran-Borane Complex; Borane Tetrahydrofuranate; Borane-Tetrahydrofuran Adduct; Borane-Tetrahydrofuran Solution; THF-Borane; Borane, compd. with tetrahydrofuran (1:1)
EINECS	237-862-4

Quality Control

Our Borane-Tetrahydrofuran Complex is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets precise specifications for concentration, purity, and stability. A comprehensive Certificate of Analysis (COA) detailing assay results, impurity profiles, and physical properties is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (nitrogen or argon) in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials. Due to its highly volatile and easily oxidized nature, the container must be kept tightly sealed and handled with appropriate precautions to prevent exposure to moisture and air. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to slightly yellow solution
Identification (IR)	Conforms
Assay (Borane, as BH3)	≥ 1.0 M in THF
Purity (HPLC/GC)	Contact for details
Water Content (KF)	< 0.1%
Peroxide (as H2O2)	< 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.