Description

5-Chloro-1-Isobutyl-2-Isopropyl-1H-Imidazole is a specialized, high-purity heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique substituted imidazole structure makes it a valuable intermediate for the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral medications.
• Agrochemical Synthesis: Used in the development of modern fungicides, herbicides, and plant growth regulators, where the imidazole core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized N-heterocyclic carbene (NHC) precursors and other organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, ionic liquids, and metal-organic frameworks (MOFs) due to its tunable electronic properties.
• Custom Chemical Synthesis: A versatile building block for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	5-Chloro-1-Isobutyl-2-Isopropyl-1H-Imidazole
CAS No.	14040-88-1
Molecular Formula	C10H17ClN2
Molecular Weight	200.71 g/mol
Synonyms	5-Chloro-1-(2-methylpropyl)-2-(1-methylethyl)-1H-imidazole; 1H-Imidazole, 5-chloro-1-(2-methylpropyl)-2-(1-methylethyl)-; 5-Chloro-1-isobutyl-2-isopropylimidazole; 14040-88-1; AI3-52698; NSC 163045; 2-Isopropyl-5-chloro-1-isobutylimidazole; 1-Isobutyl-2-isopropyl-5-chloroimidazole
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-Isobutyl-2-Isopropyl-1H-Imidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.