Description

(-)-Praeruptorin A CAS NO 14017-71-1 is a high-purity, optically active coumarin derivative isolated from traditional medicinal plants. This compound serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate for research and development in modern pharmacology. It is primarily sought by pharmaceutical researchers, analytical laboratories, and manufacturers developing novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal extracts and finished pharmaceutical products in quality control laboratories.
• Bioactive Compound Research: Serves as a key intermediate or lead compound in pharmacological studies targeting inflammation, cardiovascular diseases, and cancer.
• Natural Product Chemistry: Employed in academic and industrial research for studying the structure-activity relationships (SAR) of coumarin derivatives.
• Analytical Method Development: Essential for developing and validating chromatographic methods (e.g., HPLC, LC-MS) for the detection of praeruptorins in complex matrices.
• Nutraceutical Standardization: Used to standardize and authenticate botanical dietary supplements derived from Peucedanum praeruptorum and related species.

Basic Information

Product Name	(-)-Praeruptorin A
CAS No.	14017-71-1
Molecular Formula	C₂₁H₂₂O₇
Molecular Weight	386.40 g/mol
Synonyms	Praeruptorin A; (-)-Praeruptorin A; d-Praeruptorin A; (3'S,4'S)-3',4'-Disenecioyloxy-3',4'-dihydroseselin; Pd-Ia; ANGELICIN, 8-(2,3-DIHYDROXY-3-METHYLBUTOXY)-4,5-DIMETHOXY-7-[(3-METHYL-1-OXO-2-BUTEN-1-YL)OXY]-, (2S,3S)-; 7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE, 9-(2,3-DIHYDROXY-3-METHYLBUTOXY)-4-METHOXY-2-OXO-2H,8H-BENZO[1,2-B:3,4-B']DIPYRAN-8-YL 3-METHYL-2-BUTENOATE, (2S,3S)-
EINECS	Contact for details

Quality Control

Our (-)-Praeruptorin A is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.