Description

2-Thiophene-5-D-Carboxylic Acid is a specialized deuterated building block of significant interest in advanced chemical synthesis. This compound matters for its role in the development of labeled compounds, where the deuterium atoms provide unique properties for analytical and research applications. It is primarily needed by pharmaceutical researchers, agrochemical developers, and material scientists working on deuterium-labeled active ingredients, metabolic studies, and high-performance organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of deuterated drug candidates for improved metabolic stability and pharmacokinetic profiling.
• Agrochemical Research: Used in developing labeled analogs of pesticides and herbicides for environmental fate and metabolism studies.
• Material Science: Serves as a building block for deuterated conjugated polymers and organic semiconductors in OLED and OFET research.
• Analytical Chemistry: Employed as an internal standard or reference compound in mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.
• Metabolic Pathway Tracing: Facilitates the study of biochemical pathways and drug metabolism in vivo using deuterium as a stable isotopic tracer.
• Chemical Biology: Utilized in probe development for investigating protein-ligand interactions and enzyme mechanisms.

Basic Information

Product Name	2-Thiophene-5-D-Carboxylic Acid
CAS No.	13999-11-6
Molecular Formula	C5H3DO2S
Molecular Weight	129.15 g/mol
Synonyms	5-Deutero-2-thiophenecarboxylic Acid; 2-Thiophenecarboxylic-5-d Acid; 5-Deuterothiophene-2-carboxylic Acid; Deutero-thiophene carboxylic acid; Thiophene-2-carboxylic-5-d acid; 2-Carboxy-5-deuterothiophene; 5-D-Thiophene-2-carboxylic Acid; 13999-11-6
EINECS	Contact for details

Quality Control

Our 2-Thiophene-5-D-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR for deuterium incorporation and HPLC/GC for chemical purity and identity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Content (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.