Description

1-p-Tolyl-1H-Tetrazole-5-Thiol is a versatile sulfur-containing heterocyclic compound that serves as a key building block and reagent in advanced chemical synthesis. Its value lies in its unique reactivity as a thiol and the structural properties of the tetrazole ring, making it a critical intermediate for specialized applications. This product is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring tetrazole or thiol functional groups for bioactivity or as a bioisostere for carboxylic acids.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides, where the tetrazole moiety can enhance biological activity and stability.
• Polymer Chemistry & Material Science: Acts as a chain transfer agent (CTA) or functional monomer in radical polymerization processes, and as a ligand or precursor for metal-organic frameworks (MOFs) and other advanced materials.
• Corrosion Inhibition: Utilized in formulations for metal surface treatments and coatings, where its molecular structure can provide effective corrosion protection.
• Chemical Research & Development: Employed as a versatile reagent in organic synthesis for constructing complex molecules, including in click chemistry and heterocycle formation.

Basic Information

Product Name	1-p-Tolyl-1H-Tetrazole-5-Thiol
CAS No.	13980-77-3
Molecular Formula	C8H8N4S
Molecular Weight	192.24 g/mol
Synonyms	5-Mercapto-1-p-tolyl-1H-tetrazole; 1-(4-Methylphenyl)-1H-tetrazole-5-thiol; 1-(p-Tolyl)-1H-tetrazole-5-thiol; 5-Thiol-1-p-tolyltetrazole; 1-(4-Methylphenyl)-1H-tetrazole-5-thione; PTET; 4-Methyl-1-(1H-tetrazol-5-ylsulfanyl)benzene (tautomer); 5-Mercapto-1-(4-methylphenyl)-1H-tetrazole
EINECS	Contact for details

Quality Control

Our 1-p-Tolyl-1H-Tetrazole-5-Thiol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance in regulated research and manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	198°C - 202°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.