Description

Trimethyl-D9-Amine is a deuterated analog of trimethylamine, where nine hydrogen atoms are replaced with deuterium. This high isotopic purity makes it an essential internal standard and tracer in advanced analytical chemistry and metabolic research. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications requiring precise quantification and mechanistic studies.

Application

• NMR Spectroscopy: Serves as a crucial internal standard and chemical shift reference in proton and carbon-13 NMR analysis.
• Mass Spectrometry (MS): Used as a stable isotope-labeled internal standard for the accurate quantification of trimethylamine and related compounds in LC-MS and GC-MS methods.
• Metabolic Pathway Tracing: Enables the study of choline, carnitine, and microbial metabolism in biomedical and nutritional research.
• Pharmaceutical Development: Acts as a labeled precursor or intermediate in the synthesis of deuterated drug candidates for pharmacokinetic and metabolic stability studies.
• Chemical Reaction Mechanism Studies: Utilized in kinetic isotope effect (KIE) experiments to elucidate reaction pathways and mechanisms.
• Environmental and Food Analysis: Supports method development for detecting trace levels of trimethylamine and its derivatives in complex matrices.

Basic Information

Product Name	Trimethyl-D9-Amine
CAS No.	13960-80-0
Molecular Formula	C3D9N
Molecular Weight	68.15 g/mol
Synonyms	Perdeuterotrimethylamine; Trimethylamine-d9; N,N-Dimethylmethanamine-d9; TMA-d9; (CD3)3N; Deuterated Trimethylamine; Trimethylamine (D9); N-Trimethyl-d9-amine
EINECS	Contact for details

Quality Control

Every batch of Trimethyl-D9-Amine is produced and tested under strict quality management protocols to ensure exceptional isotopic and chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % D), chemical purity, and solvent residues. Our quality systems support compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at 2-8°C. The container must be kept tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Isotopic Enrichment (Atom % D)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.