Description

4,5α-Epoxy-17-Methyl-6α-Piperidinomorphinan-3-Ol is a high-purity synthetic opioid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of specialized analgesics and for in-depth pharmacological studies targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of novel therapeutic agents and analytical reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent opioid analgesics and related therapeutic compounds.
• Pharmacological Research: Used as a reference standard and active agent in studies investigating opioid receptor binding, activity, and signal transduction pathways.
• Analytical Chemistry: Serves as a high-purity standard for method development and validation in chromatographic (HPLC, GC) and spectroscopic analyses.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to design and evaluate new molecules with modified pharmacological profiles.
• Controlled Substance Analog Research: Used in forensic and regulatory science for the identification and characterization of novel synthetic opioids.

Basic Information

Product Name	4,5α-Epoxy-17-Methyl-6α-Piperidinomorphinan-3-Ol
CAS No.	13851-14-4
Molecular Formula	C23H30N2O2
Molecular Weight	366.50 g/mol
Synonyms	6α-Piperidinomorphinan-3-ol, 4,5α-epoxy-17-methyl-; 17-Methyl-4,5α-epoxy-6α-piperidinomorphinan-3-ol; 4,5α-Epoxy-17-methyl-6α-piperidinomorphinan-3-ol; 6α-Piperidinomorphinan-3-ol, 4,5α-epoxy-17-methyl- (8CI); 4,5α-Epoxy-17-methyl-6α-piperidinomorphinan-3-ol; 13851-14-4; 17-Methyl-4,5α-epoxy-6α-piperidinomorphinan-3-ol
EINECS	Contact for details

Quality Control

Our 4,5α-Epoxy-17-Methyl-6α-Piperidinomorphinan-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and residual solvent analysis by GC, to ensure it meets exacting standards for research use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.