Description

5-Methoxy-7-Nitro-1H-Indole-2-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both electron-donating and electron-withdrawing substituents, makes it an essential precursor for developing novel pharmaceuticals and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology: Employed as a fluorescent probe or a tagging reagent in biochemical assays and diagnostic research.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological development and exploratory synthesis projects.

Basic Information

Product Name	5-Methoxy-7-Nitro-1H-Indole-2-Carboxylic Acid Ethyl Ester
CAS No.	13838-44-3
Molecular Formula	C₁₂H₁₂N₂O₅
Molecular Weight	264.24 g/mol
Synonyms	Ethyl 5-Methoxy-7-nitro-1H-indole-2-carboxylate; 7-Nitro-5-methoxyindole-2-carboxylic acid ethyl ester; 1H-Indole-2-carboxylic acid, 5-methoxy-7-nitro-, ethyl ester; 5-Methoxy-7-nitroindole-2-carboxylic acid ethyl ester; 13838-44-3; Ethyl 5-methoxy-7-nitroindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Methoxy-7-Nitro-1H-Indole-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.