Description

4-Hydroxy-6-Methoxy-3-Nitrocoumarin is a functionalized coumarin derivative, a versatile heterocyclic building block prized for its unique photophysical and chemical reactivity. This compound matters as a key synthetic intermediate for developing advanced materials, including fluorescent dyes, optical brighteners, and active pharmaceutical ingredients (APIs). It is needed by research institutions and industrial manufacturers in the fine chemical, agrochemical, and pharmaceutical sectors for creating novel compounds with specialized properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting specific enzyme inhibition.
• Fluorescent Probe & Dye Synthesis: Used in the development of fluorescent markers, sensors, and dyes due to the inherent photophysical properties of the coumarin core, which can be fine-tuned by the nitro and methoxy substituents.
• Agrochemical Research: Acts as a building block for creating new herbicides, fungicides, or plant growth regulators, leveraging its bioactivity as a functionalized heterocycle.
• Organic Synthesis & Material Science: Employed as a specialized monomer or intermediate for synthesizing advanced organic materials, polymers, or ligands for metal-organic frameworks (MOFs).
• Analytical Chemistry: Can be utilized as a standard or reagent in chromatographic methods or as a core structure for developing chemosensors.

Basic Information

Product Name	4-Hydroxy-6-Methoxy-3-Nitrocoumarin
CAS No.	13836-21-0
Molecular Formula	C₁₀H₇NO₆
Molecular Weight	237.17 g/mol
Synonyms	3-Nitro-4-hydroxy-6-methoxycoumarin; 4-Hydroxy-6-methoxy-3-nitro-2H-chromen-2-one; 6-Methoxy-4-hydroxy-3-nitrocoumarin; 3-Nitro-4-hydroxy-6-methoxy-2H-1-benzopyran-2-one; 4-Hydroxy-6-methoxy-3-nitro-1-benzopyran-2-one; 13836-21-0; NSC 403796
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-6-Methoxy-3-Nitrocoumarin is produced under a stringent quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and product integrity for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.