Description

3-Cyanomethylthiophene is a versatile heterocyclic building block featuring both a thiophene ring and a reactive cyanomethyl functional group. This unique structure makes it a critical intermediate for synthesizing complex molecules in advanced research and industrial chemistry. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for the development of active ingredients, functional polymers, and novel electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thiophene-based heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the thiophene moiety imparts specific biological activity.
• Material Science & Organic Electronics: Serves as a monomer or building block for conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand & Catalyst Development: Employed in the creation of novel ligands for metal catalysis and organocatalysts due to its electron-rich thiophene ring.
• Fine Chemical Synthesis: A versatile synthon for constructing complex molecules in custom synthesis and research-scale projects.
• Dye & Pigment Manufacturing: Intermediate in the production of specialized dyes and pigments where the cyano group facilitates further chemical modifications.

Basic Information

Product Name	3-Cyanomethylthiophene
CAS No.	13781-53-8
Molecular Formula	C6H5NS
Molecular Weight	123.17 g/mol
Synonyms	3-Thiopheneacetonitrile; (3-Thienyl)acetonitrile; 3-Thienylacetonitrile; Thiophene-3-acetonitrile; 3-(Cyanomethyl)thiophene; 2-(Thiophen-3-yl)acetonitrile; 3-Thiophenemethyl cyanide
EINECS	Contact for details

Quality Control

Our 3-Cyanomethylthiophene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.