Description

2-Iodo-5-Phenylthiophene is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the construction of complex molecules, particularly in materials science and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and organic electronics industries for cross-coupling reactions and the synthesis of functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those containing thiophene scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactivity for structure-activity relationship (SAR) studies.
• Organic Electronic Materials: Acts as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings to form biaryl and extended π-conjugated systems.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies and the exploration of new synthetic pathways involving halogenated heterocycles.

Basic Information

Item	Detail
Product Name	2-Iodo-5-Phenylthiophene
CAS No.	13781-37-8
Molecular Formula	C10H7IS
Molecular Weight	286.13 g/mol
Synonyms	5-Phenyl-2-iodothiophene; 2-Iodo-5-phenylthiophene; Thiophene, 2-iodo-5-phenyl-; 5-Phenylthiophene-2-iodide; (5-Phenylthiophen-2-yl)iodide
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-5-Phenylthiophene is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.