Description

Ethyl 5-Chloro-1-Benzothiophene-2-Carboxylate is a high-purity organic building block and key synthetic intermediate. This compound is valued for its role in constructing complex heterocyclic frameworks, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Serves as a key building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the research and development of organic semiconductors, liquid crystals, and advanced polymers due to its benzothiophene core.
• Chemical Synthesis: Acts as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Stille) for creating complex, functionalized molecules.
• Academic & Institutional R&D: Employed in university and government laboratories for fundamental research in organic chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	Ethyl 5-Chloro-1-Benzothiophene-2-Carboxylate
CAS No.	13771-67-0
Molecular Formula	C11H9ClO2S
Molecular Weight	240.70 g/mol
Synonyms	5-Chloro-1-benzothiophene-2-carboxylic acid ethyl ester; Ethyl 5-chlorobenzo[b]thiophene-2-carboxylate; 5-Chlorobenzo[b]thiophene-2-carboxylic Acid Ethyl Ester; 2-Carbethoxy-5-chlorobenzothiophene; 13771-67-0; Benzo[b]thiophene-2-carboxylic acid, 5-chloro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-1-Benzothiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.