Description

1,4-Di(Methyl-D3)-Naphthalene is a deuterated derivative of naphthalene, specifically labeled on the methyl groups of the 1,4-dimethylnaphthalene structure. This compound is of significant value as a stable isotope-labeled internal standard for analytical chemistry, ensuring precise quantification and method validation in mass spectrometry. It is primarily required by research institutions, pharmaceutical developers, and analytical laboratories engaged in metabolomics, environmental analysis, and pharmacokinetic studies where high-fidelity tracing is essential.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical reference compound in LC-MS and GC-MS analyses for the accurate quantification of dimethylnaphthalene isomers and related polycyclic aromatic hydrocarbons (PAHs).
• Pharmaceutical Research & Drug Metabolism: Used in pharmacokinetic and ADME (Absorption, Distribution, Metabolism, Excretion) studies to track drug compounds and their metabolites with high specificity.
• Environmental & Petrochemical Analysis: Enables precise measurement of PAH contaminants in soil, water, and air samples, as well as in complex hydrocarbon mixtures.
• Metabolomics & Biomarker Discovery: Facilitates the identification and quantification of endogenous metabolites in biological fluids for disease research.
• NMR Spectroscopy: Acts as a useful probe in nuclear magnetic resonance studies due to the distinct properties of deuterium atoms.
• Chemical Synthesis & Tracing: Employed as a labeled building block in synthetic organic chemistry to trace reaction pathways and mechanisms.

Basic Information

Product Name	1,4-Di(Methyl-D3)-Naphthalene
CAS No.	13720-08-6
Molecular Formula	C₁₂D₆H₈
Molecular Weight	170.25 g/mol
Synonyms	1,4-Bis(trideuteriomethyl)naphthalene; Naphthalene, 1,4-bis(methyl-d3)-; 1,4-Dimethyl-d6-naphthalene; Deuterated 1,4-Dimethylnaphthalene; 1,4-Dimethylnaphthalene-d6; 1,4-(CD3)2C10H6; Isotope Labeled 1,4-DMN
EINECS	Contact for details

Quality Control

Our 1,4-Di(Methyl-D3)-Naphthalene is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analysis to ensure high isotopic purity and chemical integrity, critical for its function as an analytical standard. A Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and solvent residues is provided with every shipment to guarantee traceability and consistency for your research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere if possible to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.