Description

Diethyl Trimethylsilyl Phosphite is a versatile organosilicon reagent primarily used as a key intermediate in the synthesis of complex organic molecules and advanced materials. Its value lies in its ability to act as a protected phosphite source and a silylating agent, facilitating critical transformations in challenging synthetic pathways. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, where it enables the production of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleotide analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of organophosphate-based pesticides, herbicides, and plant growth regulators.
• Ligand & Catalyst Preparation: Serves as a precursor for phosphite ligands used in homogeneous catalysis, including cross-coupling reactions.
• Polymer Modification: Employed as a functionalization agent to introduce phosphonate or silyl groups into polymer backbones for flame retardancy or adhesion promotion.
• Peptide & Oligonucleotide Chemistry: Utilized as a phosphorylating or protecting group agent in the solid-phase synthesis of biomolecules.
• Material Science: Intermediate in the creation of silicon-containing coatings, adhesives, and electronic materials.

Basic Information

Product Name	Diethyl Trimethylsilyl Phosphite
CAS No.	13716-45-5
Molecular Formula	C7H19O3PSi
Molecular Weight	210.29 g/mol
Synonyms	Diethyl (Trimethylsilyl) Phosphite; Phosphorous Acid, Diethyl Trimethylsilyl Ester; (Diethoxyphosphinyloxy)trimethylsilane; Trimethylsilyl Diethyl Phosphite; O-Trimethylsilyl Diethyl Phosphite; Diethoxy(trimethylsiloxy)phosphine; Diethyl P-trimethylsilyl Phosphite
EINECS	Contact for details

Quality Control

Our Diethyl Trimethylsilyl Phosphite is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.