Description

Bis(4-Methoxyphenyl)Chlorophosphine CAS NO 13685-30-8 is a versatile organophosphorus compound characterized by its chlorophosphine core flanked by two methoxyphenyl groups. This structure makes it a valuable key intermediate in the synthesis of complex molecules, particularly in advanced material science and pharmaceutical research. It is primarily sought after by R&D chemists and process development teams in the fine chemical, agrochemical, and pharmaceutical industries for constructing ligands and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those requiring phosphine-based ligands or functional groups.
• Ligand Synthesis: Used to prepare specialized phosphine ligands for catalysis in asymmetric synthesis and cross-coupling reactions (e.g., Suzuki, Heck).
• Agrochemical Production: Serves as a precursor in the manufacture of certain pesticides and herbicides where the phosphine moiety is integral to biological activity.
• Material Science Research: Employed in the development of advanced polymers, flame retardants, and electronic materials.
• Organic Synthesis Reagent: Acts as a phosphorylating or chlorinating agent in multi-step synthetic routes for complex organic molecules.
• Coordination Chemistry: Used to create metal complexes for catalytic applications and material studies.

Basic Information

Product Name	Bis(4-Methoxyphenyl)Chlorophosphine
CAS No.	13685-30-8
Molecular Formula	C14H14ClO2P
Molecular Weight	280.68 g/mol
Synonyms	Chlorobis(4-methoxyphenyl)phosphine; Bis(p-methoxyphenyl)chlorophosphine; (4-Methoxyphenyl)2PCl; p-Anisyl Chlorophosphine; Chlorodi(4-methoxyphenyl)phosphine; Di(4-methoxyphenyl)chlorophosphine; Di(p-methoxyphenyl)chlorophosphine; Phosphinous chloride, bis(4-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our Bis(4-Methoxyphenyl)Chlorophosphine is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from incompatible materials such as strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.