Description

Bis(4-Methylphenyl)Chlorophosphine is a versatile organophosphorus compound widely used as a key intermediate in advanced chemical synthesis. Its primary value lies in its role as a precursor for ligands and catalysts, enabling critical transformations in pharmaceutical and materials science research. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug research.
• Ligand Precursor: Used to synthesize phosphine-based ligands for transition metal catalysis, enabling cross-coupling and hydrogenation reactions.
• Agrochemical Synthesis: Serves as an intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Employed in the creation of flame-retardant additives and as a monomer for specialty polymers with tailored properties.
• Material Science: Used in the surface modification of nanoparticles and the development of advanced coatings and electronic materials.
• Organic Synthesis Reagent: Functions as a phosphorylating agent and a key reactant in the formation of P-C and P-N bonds for complex molecule assembly.

Basic Information

Product Name	Bis(4-Methylphenyl)Chlorophosphine
CAS No.	13685-23-9
Molecular Formula	C14H14ClP
Molecular Weight	248.68 g/mol
Synonyms	Chlorobis(4-methylphenyl)phosphine; Bis(p-tolyl)chlorophosphine; Chlorodi-p-tolylphosphine; p-Tolylphosphonous Dichloride (related); Di-p-tolylchlorophosphine; (4-Methylphenyl)phosphonous Chloride (derivative); DTCP; Phosphinous chloride, bis(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our Bis(4-Methylphenyl)Chlorophosphine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use to exclude moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.