Description

3-Chloro-2-Oxopropylidene Triphenylphosphorane is a specialized organophosphorus reagent, widely recognized as a key building block in advanced organic synthesis. Its primary value lies in its role as a versatile ylide for the synthesis of complex heterocycles and functionalized alkenes via Wittig and related reactions. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing novel molecular architectures.

Application

• As a key Wittig reagent for the synthesis of α,β-unsaturated carbonyl compounds and heterocyclic systems.
• Intermediate in the production of active pharmaceutical ingredients (APIs), particularly for molecules containing chlorinated vinyl or heterocyclic motifs.
• Building block for advanced agrochemicals, including herbicides and plant growth regulators.
• Precursor in materials science for the synthesis of functionalized polymers and organic electronic materials.
• Reagent in academic and industrial research for methodology development in organophosphorus chemistry.
• Used in the synthesis of natural product analogs and complex bioactive molecules.

Basic Information

Product Name	3-Chloro-2-Oxopropylidene Triphenylphosphorane
CAS No.	13605-66-8
Molecular Formula	C21H18ClOP
Molecular Weight	352.79 g/mol
Synonyms	(3-Chloro-2-oxopropylidene)triphenylphosphorane; 3-Chloro-2-oxopropylidenetriphenylphosphorane; 1-Chloro-3-(triphenylphosphoranylidene)acetone; 3-Chloro-2-oxopropylidenetriphenyl-λ5-phosphane; (3-Chloro-2-oxopropylidene)triphenyl-λ5-phosphane; Chloroacetone triphenylphosphorane ylide; Triphenyl(3-chloro-2-oxopropylidene)phosphorane
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Oxopropylidene Triphenylphosphorane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.