Description

Phytosphingosine CAS NO 13552-11-9 is a high-purity, naturally occurring sphingoid base that serves as a fundamental building block for ceramides and other bioactive sphingolipids. Its significance lies in its critical role as a key intermediate for synthesizing advanced skincare actives and pharmaceutical compounds, offering superior stability and bioactivity. This product is essential for manufacturers in the cosmetics, personal care, and pharmaceutical industries seeking to develop high-performance moisturizing, barrier-repair, and anti-aging formulations.

Application

• Cosmetic & Skincare Actives: Primary raw material for the synthesis of phytoceramides and pseudoceramides used in premium moisturizers, anti-aging serums, and barrier repair creams.
• Pharmaceutical Intermediates: Key starting material in the production of sphingolipid-based drugs and therapeutic agents targeting dermatological conditions and cellular signaling pathways.
• Hair Care Formulations: Incorporated into conditioners and treatments to improve hair strength, shine, and manageability by mimicking natural lipid structures.
• Biochemical Research: Used as a standard or reagent in lipidomics research, cell biology studies, and the investigation of sphingolipid metabolism.
• Advanced Delivery Systems: Utilized in the development of liposomes and other nano-carriers for enhanced topical delivery of active ingredients.

Basic Information

Product Name	Phytosphingosine
CAS No.	13552-11-9
Molecular Formula	C18H39NO3
Molecular Weight	317.51 g/mol
Synonyms	D-ribo-Phytosphingosine; (2S,3S,4R)-2-Amino-1,3,4-octadecanetriol; 4-Hydroxysphinganine; 4-Hydroxy-D-erythro-sphinganine; Phytosphingosine HCl (salt form); PHS; CosmeSphingosine™ (trade name variant)
EINECS	236-935-8

Quality Control

Our Phytosphingosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for cosmetic and pharmaceutical-grade intermediates. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	97°C - 102°C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	+4.0° to +6.0° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.