Description

Periodic Acid is a powerful oxidizing agent and a key analytical reagent in organic chemistry. Its primary commercial value lies in its unique ability to cleave carbon-carbon bonds in vicinal diols, making it indispensable for structural elucidation and synthesis. This product is essential for R&D laboratories, analytical service providers, and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise oxidative cleavage reactions.

Application

• Malaprade Reaction (Glycol Cleavage): The definitive method for the oxidative cleavage of 1,2-diols to generate aldehydes or ketones, critical for carbohydrate and polymer analysis.
• Pharmaceutical Intermediate Synthesis: Used in the selective oxidation and degradation steps during the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Analytical Chemistry & Biochemistry: A fundamental reagent for determining the structure of sugars, polysaccharides, and other polyhydroxy compounds via periodate oxidation studies.
• Microscopy & Histology: Employed as an oxidizing agent in staining techniques and for the preparation of tissue samples.
• Electronics Industry: Used in etching and surface treatment processes for specialized electronic materials.
• Research & Development: Serves as a versatile tool in academic and industrial R&D for exploring new synthetic pathways and material modifications.

Basic Information

Product Name	Periodic Acid
CAS No.	13445-51-7
Molecular Formula	H5IO6
Molecular Weight	227.94 g/mol
Synonyms	Paraperiodic Acid; Iodic(VII) Acid; Orthoperiodic Acid; Hydrogen Periodate; Periodate; HIO4·2H2O (common hydrate form)
EINECS	236-630-4

Quality Control

Our Periodic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for demanding laboratory and industrial applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming key parameters such as assay, impurity profile, and clarity of solution. We support compliance with various pharmacopeial and reagent-grade specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, the container must be kept tightly sealed when not in use to minimize exposure to atmospheric moisture and air. Store away from incompatible materials such as strong reducing agents and organic compounds.

Specification

Item	Specification
Appearance	White crystalline solid
Identification (IR)	Conforms
Assay (H5IO6)	≥ 99.0 %
Clarity of Solution	Clear and colorless
Chloride (Cl)	≤ 0.001 %
Sulfate (SO4)	≤ 0.005 %
Heavy Metals (as Pb)	≤ 0.001 %
Iron (Fe)	≤ 0.001 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.