Description

n-Acetyl-3-Hydroxykynurenine is a key intermediate metabolite in the tryptophan degradation pathway, specifically within the kynurenine route. This compound is of significant interest for its role in biochemical research and its potential as a precursor for synthesizing other biologically active molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, life sciences, and fine chemical sectors for applications ranging from metabolic studies to the development of novel therapeutic agents.

Application

• Biochemical Research: A critical standard and intermediate for studying the kynurenine pathway, tryptophan metabolism, and related neurological processes.
• Pharmaceutical Development: Serves as a key building block or reference compound in the synthesis and research of potential neuroprotective agents, immunomodulators, and drugs targeting metabolic disorders.
• Diagnostic Reagent Manufacturing: Used in the production of reagents and assay kits for quantifying metabolic pathway activity in clinical and research settings.
• Reference Standard: Employed as a high-purity certified reference material (CRM) for analytical method development, validation, and quality control in laboratories.
• Enzymology Studies: Acts as a substrate or product in enzymatic assays for studying the activity of enzymes like kynurenine 3-monooxygenase (KMO).
• Fine Chemical Synthesis: An important chiral intermediate for the custom synthesis of more complex, specialized organic compounds.

Basic Information

Item	Detail
Product Name	n-Acetyl-3-Hydroxykynurenine
CAS No.	13384-36-6
Molecular Formula	C13H14N2O6
Molecular Weight	294.26 g/mol
Synonyms	3-Hydroxy-N-acetylkynurenine; N-Acetyl-3-hydroxykynurenine; Nα-Acetyl-L-3-hydroxykynurenine; 2-Acetamido-3-(3-hydroxyanthraniloyl)propanoic Acid; (2S)-2-Acetamido-3-[(3-hydroxyphenyl)formamido]propanoic Acid; L-3-Hydroxykynurenine N-acetate; A metabolite of tryptophan
EINECS	Contact for details

Quality Control

Our n-Acetyl-3-Hydroxykynurenine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.