Description

1-Acetamido(1H-Indol-2-Yl)Methyl3-Ethyl2-Ethylmalonate is a specialized, high-purity organic building block featuring a complex molecular architecture that combines indole and malonate functionalities. This compound matters as a critical intermediate for the synthesis of advanced pharmaceutical agents and bioactive molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel therapeutic candidates or complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of new-generation pesticides and plant growth regulators.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals and dyes.
• Bioconjugation & Probe Development: Potential use in creating fluorescent probes or bioconjugates for biochemical research due to its reactive sites.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Acetamido(1H-Indol-2-Yl)Methyl3-Ethyl2-Ethylmalonate
CAS No.	13373-31-4
Molecular Formula	C20H24N2O5
Molecular Weight	372.42 g/mol
Synonyms	1-Acetamido(1H-indol-2-yl)methyl 3-ethyl 2-ethylmalonate; 2-Ethyl 3-ethyl 2-[(1H-indol-2-yl)(acetylamino)methyl]propanedioate; Ethyl 2-[(acetylamino)(1H-indol-2-yl)methyl]-2-ethylmalonate; 1-Acetamido(1H-Indol-2-Yl)Methyl 3-Ethyl 2-Ethyl Malonate; Propanedioic acid, 2-[(acetylamino)(1H-indol-2-yl)methyl]-2-ethyl-, 1,3-diethyl ester; Diethyl 2-[(acetylamino)(1H-indol-2-yl)methyl]-2-ethylmalonate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity research chemicals. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.