Description

S-(3-Aminopropyl)Thiosulfuric Acid Ester is a specialized organosulfur compound featuring both a reactive thiosulfate (Bunte salt) and a primary amine functional group. This unique bifunctional structure makes it a valuable intermediate for introducing sulfhydryl groups or creating stable thioether linkages in various synthetic pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and polymer industries for applications requiring controlled cross-linking or surface modification.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, particularly those requiring thioether or disulfide bonds for activity or stability.
• Bioconjugation Reagent: Used for modifying proteins, peptides, and antibodies by introducing free thiol groups or creating stable linkages with maleimide-functionalized molecules.
• Polymer Modification & Cross-linking Agent: Imparts functional thiol groups to polymer backbones for further reaction or acts as a cross-linker in the production of specialty resins and hydrogels.
• Surface Functionalization: Employed to create self-assembled monolayers (SAMs) or to modify material surfaces (e.g., gold, silica) with amine-reactive sites via the thiosulfate group.
• Chemical Synthesis: Serves as a protected or latent thiol source in multi-step organic syntheses, where the thiosulfate ester can be cleaved under mild conditions.

Basic Information

Product Name	S-(3-Aminopropyl)Thiosulfuric Acid Ester
CAS No.	13286-24-3
Molecular Formula	C3H9NO3S2
Molecular Weight	171.24 g/mol
Synonyms	3-Aminopropyl thiosulfate; S-(3-Aminopropyl) sodium thiosulfate; 3-Aminopropyl Bunte salt; Sodium S-(3-aminopropyl)thiosulfate; 3-Aminopropanethiosulfuric acid; Aminoalkyl thiosulfate; Thiosulfuric acid S-(3-aminopropyl) ester
EINECS	Contact for details

Quality Control

Our production of S-(3-Aminopropyl)Thiosulfuric Acid Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support cGMP-compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/Titration)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.