Description

2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Bromide is a high-purity, protected glycosyl bromide derivative, a critical building block in synthetic carbohydrate chemistry. Its primary value lies in its role as a key glycosyl donor for the stereoselective construction of complex oligosaccharides and glycoconjugates. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly for the development of novel therapeutics, vaccines, and diagnostic agents.

Application

• Glycosylation Reactions: Serves as a crucial mannosyl donor in the synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediates: Used in the research and production of carbohydrate-based drugs, including antiviral and anticancer agents.
• Glycoconjugate Synthesis: Key precursor for creating glycoproteins, glycolipids, and neoglycoconjugates for biological studies.
• Vaccine Development: Employed in the synthesis of carbohydrate antigens for conjugate vaccine candidates.
• Chemical Biology Probes: Used to create labeled or modified sugars for studying carbohydrate-protein interactions and metabolic pathways.
• Process Development: A standard reagent for scaling up glycosylation processes in pilot plants and commercial manufacturing.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Bromide
CAS No.	13242-53-0
Molecular Formula	C14H19BrO9
Molecular Weight	411.20 g/mol
Synonyms	α-D-Mannopyranosyl Bromide 2,3,4,6-Tetraacetate; Tetra-O-acetyl-α-D-mannopyranosyl Bromide; 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl Bromide; AcOBrMan; Bromo(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl); α-D-Mannosyl Bromide Tetraacetate; 1-Bromo-2,3,4,6-tetra-O-acetyl-α-D-mannopyranose
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and moisture content, supporting applications in GMP and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or inert atmosphere to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.