Description

Isopropylphenylphosphinyl Chloride is a versatile organophosphorus reagent, specifically a phosphinic chloride derivative. This compound is a critical building block in the synthesis of complex molecules, offering a reactive handle for the introduction of phosphinic acid groups. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for constructing novel active ingredients and functional ligands.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active phosphinic acid derivatives, including potential enzyme inhibitors and drug candidates.
• Agrochemical Synthesis: Used to create novel organophosphorus pesticides and herbicides with tailored properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing phosphine oxide and phosphinic acid ligands used in metal catalysis and coordination chemistry.
• Flame Retardant Precursor: Intermediate in the production of specialized organophosphorus flame retardants for polymers and textiles.
• Material Science: Building block for creating functionalized surfaces, metal-organic frameworks (MOFs), and polymers with specific chelating or catalytic properties.
• Chemical Research: A valuable reagent for method development and exploring new reaction pathways in organophosphorus chemistry.

Basic Information

Product Name	Isopropylphenylphosphinyl Chloride
CAS No.	13213-43-9
Molecular Formula	C9H12ClOP
Molecular Weight	202.62 g/mol
Synonyms	Isopropyl(phenyl)phosphinic chloride; Phenyl(isopropyl)phosphinic chloride; Isopropylphenylphosphinic chloride; (Isopropyl)(phenyl)phosphinic chloride; α-Isopropylbenzenephosphonochloridate; Benzene, (chloroisopropylphosphinyl)-; Phosphinic chloride, P-isopropyl-P-phenyl-
EINECS	Contact for details

Quality Control

Our Isopropylphenylphosphinyl Chloride is produced under stringent quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and titration to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.