Description

2-Bromo-5-Nitrothiophene is a versatile halogenated nitroheterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromine and nitro substituents on the thiophene ring, makes it a valuable electrophilic building block for constructing complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for antimicrobial, antiviral, and anti-inflammatory agents.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and nonlinear optical (NLO) materials.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysis.
• Dye and Pigment Chemistry: Intermediate in the production of specialized heterocyclic dyes and colorants.
• Academic & R&D: Fundamental reagent for methodological studies in organic synthesis, including cross-coupling and nucleophilic substitution reactions.

Basic Information

Product Name	2-Bromo-5-Nitrothiophene
CAS No.	13198-50-1
Molecular Formula	C4H2BrNO2S
Molecular Weight	208.03 g/mol
Synonyms	2-Bromo-5-nitrothiophene; 5-Nitro-2-bromothiophene; Thiophene, 2-bromo-5-nitro-; 2-Bromo-5-nitro-thiophene; 2-Bromonitrothiophene; 2-Bromo-5-nitrothiophene (stabilized); 2-Bromo-5-nitrothiophene, 97%; 2-Bromo-5-nitrothiophene (contains stabilizer)
EINECS	236-162-3

Quality Control

Our 2-Bromo-5-Nitrothiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.