Description

Thiophene, 2-Chloro-5-Nitro- CAS NO 13195-49-8 is a high-purity, halogenated nitro-thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity, enabling the construction of complex heterocyclic systems and functional materials. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Material Science Research: Acts as a monomer or functional unit in the development of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Chemical Research & Development: Employed as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to create diverse chemical libraries.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized dyes and pigments with specific light-absorption properties.

Basic Information

Product Name	Thiophene, 2-Chloro-5-Nitro-
CAS No.	13195-49-8
Molecular Formula	C4H2ClNO2S
Molecular Weight	163.58 g/mol
Synonyms	2-Chloro-5-nitrothiophene; 5-Nitro-2-chlorothiophene; 2-Chloro-5-nitrothiophene; Thiophene, 2-chloro-5-nitro-; 2-Chloro-5-nitro-thiophene; 2-Chlor-5-nitrothiophen; 2-Cl-5-NO2-Thiophene
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Nitrothiophene is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via HPLC, GC, and NMR is supplied with each shipment. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.