Description

Nitromethane-D3 is a deuterated isotopologue of nitromethane, where three hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This compound is a critical analytical standard and reagent in advanced research, particularly in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry, where it serves as a solvent and internal standard. It is essential for scientists and quality control professionals in the pharmaceutical, agrochemical, and academic research sectors who require precise isotopic labeling for mechanistic studies, metabolic pathway tracing, and method development.

Application

• NMR Spectroscopy Solvent: Used as a deuterated solvent for proton NMR, providing a non-interfering signal for accurate structural analysis of organic compounds.
• Mass Spectrometry Internal Standard: Serves as a critical internal standard or reference compound in quantitative LC-MS and GC-MS analyses due to its defined isotopic pattern.
• Mechanistic & Kinetic Studies: Employed in isotopic labeling experiments to investigate reaction mechanisms, kinetics, and metabolic pathways in pharmaceutical and chemical research.
• Deuterium Source in Synthesis: Acts as a reagent for introducing deuterium atoms into target molecules in the synthesis of labeled compounds for research and development.
• Analytical Method Development: Utilized in developing and validating sensitive analytical methods in regulatory and quality control laboratories.
• Academic & Industrial Research: A fundamental tool in university and corporate R&D departments for advanced material and life science research.

Basic Information

Product Name	Nitromethane-D3
CAS No.	13031-32-8
Molecular Formula	CD3NO2
Molecular Weight	64.07 g/mol
Synonyms	Deuterated Nitromethane; Nitromethane-d3; [2H3]Nitromethane; Trideuterionitromethane; Nitromethane (D3); Perdeuterated Nitromethane; Nitromethane-D3 99.5% D; Nitromethane (CD3NO2)
EINECS	Contact for details

Quality Control

Our Nitromethane-D3 is manufactured under strict quality systems to ensure high isotopic and chemical purity, meeting the exacting requirements of analytical and research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D atom %), chemical purity by GC or HPLC, and water content. We support compliance with relevant GMP and ISO guidelines for laboratory reagents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat, sparks, and open flames. Due to its highly volatile nature, keep container tightly sealed when not in use. Recommended storage temperature is 2-8°C to maximize stability, although it can be stored at controlled room temperature (15-25°C) for shorter periods.

Specification

Item	Specification
Appearance	Colorless Clear Liquid
Identification (IR)	Conforms
Isotopic Purity (D atom %)	≥ 99.5%
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.1%
NMR Solvent Suitability	Passes Test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.