Description

2-Bromo-1-(5-Phenyl-2-Thienyl)-1-Ethanone is a specialized organic building block featuring a bromoacetyl group attached to a phenyl-substituted thiophene core. This compound matters as a key synthetic intermediate, enabling the introduction of a reactive ketone moiety for constructing complex heterocyclic and pharmaceutical scaffolds. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and organic electronic materials.
• Chemical Synthesis: Employed in organic synthesis for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions due to the reactive bromine atom.
• Academic & R&D: A valuable reagent for methodological studies and exploring new reaction pathways in university and industrial research laboratories.

Basic Information

Product Name	2-Bromo-1-(5-Phenyl-2-Thienyl)-1-Ethanone
CAS No.	10531-43-8
Molecular Formula	C12H9BrOS
Molecular Weight	281.17 g/mol
Synonyms	2-Bromo-1-(5-phenylthiophen-2-yl)ethanone; 2-Bromo-1-(5-phenyl-2-thienyl)ethanone; 5-Phenyl-2-thienyl bromomethyl ketone; 2-Bromo-1-(5-phenyl-2-thienyl)ethan-1-one; 2-Bromo-5-phenyl-2-thienyl ketone; α-Bromo-5-phenyl-2-thienyl methyl ketone; 10531-43-8
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(5-Phenyl-2-Thienyl)-1-Ethanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems support cGMP and ISO standards for reliable, batch-to-batch consistency required for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.