Description

4-(Trimethylsilyl)Oxycinnamic Acid Trimethylsilyl Ester is a specialized organosilicon derivative of cinnamic acid, featuring dual trimethylsilyl (TMS) protecting groups. This compound is a crucial synthetic intermediate, valued for its role in protecting sensitive hydroxyl and carboxylic acid functionalities during complex organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where protection of phenolic and carboxylic acid groups is required.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate cinnamic acid derivatives.
• Organic Synthesis Reagent: Serves as a versatile protected synthon in multi-step organic reactions, including cross-coupling and condensation reactions.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoresponsive polymers where the cinnamate moiety is integral.
• Flavor & Fragrance Chemistry: Acts as a precursor in the synthesis of complex aromatic compounds for high-value fragrance applications.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploratory chemistry in university and corporate research settings.

Basic Information

Product Name	4-(Trimethylsilyl)Oxycinnamic Acid Trimethylsilyl Ester
CAS No.	10517-30-3
Molecular Formula	C15H24O3Si2
Molecular Weight	308.52 g/mol
Synonyms	4-[(Trimethylsilyl)oxy]cinnamic acid trimethylsilyl ester; Cinnamic acid, 4-(trimethylsilyl)oxy-, trimethylsilyl ester; 4-Hydroxycinnamic acid bis(trimethylsilyl) ether; Bis(trimethylsilyl) 4-hydroxycinnamate; p-(Trimethylsiloxy)cinnamic acid trimethylsilyl ester; TMS-Cinnamate (protected); 4-TMS-Oxycinnamic Acid TMS Ester
EINECS	Contact for details

Quality Control

Our 4-(Trimethylsilyl)Oxycinnamic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to prevent hydrolysis of the silyl groups.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.