Description

3-Iodothiophene is a halogenated heterocyclic compound that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in the reactivity of the iodine atom, which enables efficient cross-coupling reactions for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, particularly for developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those containing thiophene scaffolds for various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides where the thiophene moiety imparts specific biological activity.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and photovoltaic cells.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form carbon-carbon bonds.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Chemical Research & Development: A fundamental reagent for exploring new synthetic methodologies and constructing complex heterocyclic systems in academic and industrial R&D labs.

Basic Information

Product Name	3-Iodothiophene
CAS No.	10486-61-0
Molecular Formula	C4H3IS
Molecular Weight	209.04 g/mol
Synonyms	Thiophene, 3-iodo-; 3-Iodothiofuran; β-Iodothiophene; 3-Thienyl iodide; Iodothiophene; 3-Thiopheneyl iodide; 1-Iodo-3-thia-2,4-cyclopentadiene
EINECS	234-001-6

Quality Control

Every batch of our 3-Iodothiophene is produced and tested under a strict quality management system to ensure high purity, consistency, and reliability for your critical synthesis work. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.