Description

4-(4-Amino-1,3-Dioxo-1,3-Dihydro-Isoindol-2-Yl)-Butyric Acid is a high-purity, functionalized isoindoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of an amino group and a carboxylic acid moiety on a phthalimide-like core, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and sophisticated fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme inhibition or receptor modulation.
• Peptidomimetic Synthesis: Used to incorporate constrained, heterocyclic scaffolds into peptide analogs to enhance stability and biological activity.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Ligand and Chelator Development: Employed in the design of complexing agents for catalysis or metal ion sequestration.
• Agrochemical Research: Acts as a building block for developing new crop protection agents and herbicides.
• Dye and Pigment Synthesis: Utilized in the production of advanced colorants and functional dyes due to its aromatic structure.
• Bioconjugation: The carboxylic acid group facilitates coupling reactions for labeling biomolecules in diagnostic applications.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	4-(4-Amino-1,3-Dioxo-1,3-Dihydro-Isoindol-2-Yl)-Butyric Acid
CAS No.	10414-02-5
Molecular Formula	C12H12N2O4
Molecular Weight	248.24 g/mol
Synonyms	2-(3-Carboxypropyl)-4-amino-1H-isoindole-1,3(2H)-dione; 4-Amino-2-(3-carboxypropyl)isoindoline-1,3-dione; 4-Aminophthalimidobutyric Acid; γ-(4-Amino-1,3-dioxoisoindolin-2-yl)butyric Acid; 4-(4-Amino-1,3-dioxoisoindolin-2-yl)butanoic Acid; 2-(4-Carboxybutyl)-4-amino-isoindole-1,3-dione; 4-Amino-N-(3-carboxypropyl)phthalimide
EINECS	Contact for details

Quality Control

Our 4-(4-Amino-1,3-Dioxo-1,3-Dihydro-Isoindol-2-Yl)-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.